Thermoelectric cooler assemblies, often referred to as Peltier Cooler assemblies, are compact cooling units that control the temperature in a wide range of applications. Products can reach the market faster if the designer starts from a standard thermoelectric cooler assembly platform and modifies it. Thermoelectric cooler assemblies offer several advantages over other cooling technologies like compressor-based systems. They can cool to well below ambient and offer precise temperature control, achieving ±0.01°C under steady-state conditions. They are highly reliable with almost no maintenance and are mountable in any orientation. Compared to compressor-based systems, they are much lighter with a smaller footprint. In addition, government restrictions of traditional and natural refrigerants central to traditional compressor-based systems make thermoelectrics a more advantageous thermal management solution.