What is required for a standard setup? Adapt the driver to the desired motor current and power supply voltage by selecting the sense resistor values as shown in the datasheet. The TMC2209 may be used with 3.3 V as well as with 5 V I/Os to adapt to the CPU supply voltage. Connect a supply voltage to VCC_IO accordingly. For noise filtering, use a 100 nF capacitor against ground. The UART interface allows addressing of up to four ICs using MS1 and MS2 for address setting. Finally, the power supply terminals should be filtered with 100 nF capacitors as good practice. VS voltage shall be buffered by a capacitor of sufficient size in order to take over chopper ripple current. Best to choose a low-ESR capacitor of minimum 330 µF.