A system of interconnected networks with host-to-host datagram service uses the Internet Protocol (IP). The Internet Protocol Version 6 (IPv6) is the successor of IPv4 addressing standard. IPv6 is being introduced to solve IPv4 address exhaustion problems, since IPv6 uses a 128-bit numbering scheme. Conventional networks use the IP protocol as a base of many application protocols. The Internet of Things has raised the need to incorporate the sensor networks to the same ecosystem. Most wireless sensor networks use the IEEE® 802.15.4 standard for communication. This specification defines a maximum frame length of 127 bytes while IPv6 packets can be up to 1,280 bytes long. This limitation required a new standard to define the adoption and compression of IPv6 packets transmitting over IEEE® 802.15.4 data frames. This adaptation is referred to as IPv6 over Low-power WPAN (6LoWPAN). The pictures here are scenarios for a Thread 6LoWPAN frame, illustrating MAC header variations between fragmented and non-fragmented 6LoWPAN packets, the above picture here corresponds to a single-hop and the below one to a multi-hop frame format.